SCARB2 anticorps

N° du produit ABIN6567626

L’anticorps Lapin Polyclonal anti-SCARB2 a été validé pour WB. Il convient pour détecter SCARB2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SCARB2 anticorps (ABIN6567626)

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SCARB2 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human SCARB2

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000 - 1:3000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SCARB2

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Autre désignation: SCARB2

Sujet:

Synonyms: 85 kDa lysosomal membrane sialoglycoprotein,85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2,AMRF,CD36,CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II),CD36 antigen,CD36 antigen-like 2,CD36L2,EPM4,HLGP85,LGP85,LIMP 2,LIMP II,LIMP2,LIMPII,Lysosomal integral membrane protein II,Lysosome membrane protein 2,Lysosome membrane protein II,OTTHUMP00000160590,OTTHUMP00000219176,Scarb2,Scavenger receptor class B member 2,Scavenger receptor class B, member 2,SCRB2,SR BII,SRBII

Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 80kDa

Calculated_MW: 37kDa/54kDa

ID gène: 950

UniProt: Q14108